Her er et utdrag som beskriver en ny forskningsstudie. Den forklarer hvorfor noen utvikler såkalt "eple eller pære" formet kroppsform. Proteinet 11BetaHSD1 viste seg å være høyere hos personer med mer fett lagret rundt magen. Forskere leter nå etter måter å kunne hemme proteinet, for det er også linket til overvekt og diabetes.
"The latest findings give greater understanding of how the protein works, which could help development of medicines to treat obesity. Levels of the protein -- known as 11BetaHSD1 -- tend to be higher in the presence of an unhealthy type of body fat which tends to be stored around the torso -- typical of "apple-shapes." Healthier fat, linked to lower levels of the protein, tends to be stored around the hips and is used more safely by the body as a source of energy -- typical of people who are "pear-shaped."
The study found that mice with the protein in their bodies were more likely to have unhealthy fat tissue after four weeks on a high fat diet, compared with mice without the protein.
As well as being more likely to be stored around vital organs in the torso, fat with higher levels of 11BetaHSD1 is considered to be unhealthy as it is associated with an over-reaction in the immune system.
Cells normally become inflamed in order to kill off an infection, but as there is no infection in the fat tissue the inflammation instead causes damage to healthy cells."